How is the processing tolerance of Bacillus clausii?
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Update time : 2026-04-23 11:08:42
Bacillus clausii is one of the few safe and effective spore-forming probiotics in the Bacillus genus, capable of producing endospores resistant to high temperatures, acid and bile salts.
In application, Bacillus clausii is widely used in dietary supplements, functional foods and beverages. Its spores exhibit excellent tolerance to heat and industrial processing stress, as well as strong resistance to gastric acid and bile salts in the human intestinal tract.Without the need for microencapsulation, it can be easily incorporated into liquid, solid and semi-solid products without altering sensory properties.
Just how robust is the processing tolerance of Bacillus clausii?First, it features outstanding thermal stability: a survival rate of 96.31% after exposure to 90°C for 30 minutes, and still 82.76% at 100°C for 60 minutes.Second, it tolerates a wide pH range, with survival rates from 41% to 99.7% at pH 2–12, and around 60% survival after 20 minutes in gastric acid.Third, it remains stable at room temperature without refrigeration. Spores can be stored stably at ambient temperature for 24 months, requiring no cold-chain logistics, with a shelf life of up to 2 years.Fourth, microencapsulation is unnecessary. The spores naturally possess a dense multi-layer protective structure, suitable for direct use in powders, capsules, tablets, gummies, drinks and other formulations.
Multiple studies show that spores maintain viability against temperature fluctuations and shear forces during transportation, manufacturing and processing, adapting perfectly to capsules, powders, tablets, beverages, baked foods and various other production scenarios.
In application, Bacillus clausii is widely used in dietary supplements, functional foods and beverages. Its spores exhibit excellent tolerance to heat and industrial processing stress, as well as strong resistance to gastric acid and bile salts in the human intestinal tract.Without the need for microencapsulation, it can be easily incorporated into liquid, solid and semi-solid products without altering sensory properties.
Just how robust is the processing tolerance of Bacillus clausii?First, it features outstanding thermal stability: a survival rate of 96.31% after exposure to 90°C for 30 minutes, and still 82.76% at 100°C for 60 minutes.Second, it tolerates a wide pH range, with survival rates from 41% to 99.7% at pH 2–12, and around 60% survival after 20 minutes in gastric acid.Third, it remains stable at room temperature without refrigeration. Spores can be stored stably at ambient temperature for 24 months, requiring no cold-chain logistics, with a shelf life of up to 2 years.Fourth, microencapsulation is unnecessary. The spores naturally possess a dense multi-layer protective structure, suitable for direct use in powders, capsules, tablets, gummies, drinks and other formulations.
Multiple studies show that spores maintain viability against temperature fluctuations and shear forces during transportation, manufacturing and processing, adapting perfectly to capsules, powders, tablets, beverages, baked foods and various other production scenarios.
