Probiotics Powder
Lactobacillus casei Powder
Lactobacillus casei is a natural probiotic in the human intestinal tract, renowned for its excellent acid and bile salt tolerance as well as intestinal colonization capacity. It helps regulate intestinal flora, boost immunity, relieve constipation and dia
Description
What is Lactobacillus casei?
Lactobacillus casei is a Gram-positive probiotic naturally present in the human intestinal tract and oral cavity. It is famous for its acid and bile salt tolerance as well as strong intestinal colonization ability. Widely applied in fermented dairy products and dietary supplements, it delivers proven health benefits including regulating gut microbiota, enhancing immunity, improving metabolism and preventing diarrhea.
| Product Name: | Lactobacillus casei Powder |
| Strain name: | Lactobacillus casei |
| Strain identification: | Characteristic by API 50CH&16S rDNA |
| Type: | Freeze dried powder |
| Packing: | 1kg/bag, 5kg/bag in cold-chain package |
| Storage: | Package sealed at 4℃ or refrigeration - 18℃ |
| Shelf life: | 24 months from date of production |
| Certfication: | NSF, HACCP, ISO9001, Kosher, HALAL |
| Documents support: | Genetic identification report |
| IDA deposit certificate | |
| Certificate of analysis | |
| Stability study report | |
| Anti-bile salt & Anti gastro-acid study report | |
| Antibiotic sensitivity test certificate | |
| Safety study report | |
| Microbial Enumeration method |
| Descrption: | Fine powder, no caking, no abnormal odor, no visible foreign bod |
| Color: | White to light yellow |
| Mositure: | NMT 5.0% |
| Water activity: | < 0.12% |
| Viable cell count: | NLT 400 billion cfu/gram |
| Non LAB count: | < 5000 cfu/g |
| Yeast &mould: | NMT 50 cfu/g |
| Coliform: | < 10 cfu/g |
| Pathogenic bacteria: | Negative |
| Lead(Pb): | NMT 0.5 mg/kg |
| Arsenic(As): | NMT 0.5 mg/kg |
| Cadmium(Cd): | NMT 1.0 mg/kg |
| Mercury(Hg): | NMT 0.1 mg/kg |
1. Regulate Intestinal Flora and Alleviate Intestinal InflammationStrains LC2W and Zhang can significantly increase the abundance of beneficial bacteria such as Lactobacillus and Bifidobacterium, reduce pro-inflammatory factors including IL-17A, IFN-γ and TNF-α, raise short-chain fatty acid levels, and alleviate DSS-induced colitis.
2. Enhance Immunity and Shorten Respiratory Infection DurationStrain 431 (≥10⁹ CFU daily) reduced upper respiratory symptom duration from 7.3 days to 6.4 days among 1,104 healthy adults, with more prominent effects in the later stage of intervention.
3. Improve Metabolic Syndrome and Weight ManagementStrains LC2W, 431 and 01 help reduce body weight, BMI and waist circumference, improve fasting blood glucose, insulin level and insulin resistance, lower serum triglycerides, and promote lipid oxidation.
4.Protect Renal Function and Resist FibrosisStrain Zhang alleviates acute kidney injury and chronic renal fibrosis caused by bilateral renal ischemia-reperfusion, slows renal function decline in patients with chronic kidney disease, and features good tolerability.
1. Excellent Acid and Bile Salt ToleranceLactobacillus casei can withstand gastric acid (pH 2.5–3.0) and 0.3% bile salts. It passes through the gastrointestinal tract alive and colonizes the intestines, ensuring stable probiotic effects.
2. Strong Intestinal Colonization AbilityIt binds to intestinal epithelial cells via surface adhesion proteins, achieving temporary intestinal colonization to continuously regulate microbiota. It can survive for several days even after supplementation stops.
3. Diverse Strain-Specific FunctionsDifferent strains have distinct health benefits: LC2W (gut & metabolism), Zhang (anti-inflammation & kidney protection), 431 (immunity & metabolism), 01 (blood glucose regulation). Strain selection should match targeted health outcomes.
4.Facultative Anaerobe & Moderate Processing AdaptabilityIt is moderately sensitive to oxygen and humidity, requiring sealed, light-proof storage. It is suitable for fermented dairy products (symbiotic fermentation required), solid beverages and tableting processes. High temperatures (>45°C) and high humidity should be avoided.
Q1: What are the most well-known strains of Lactobacillus casei?
A: LC2W (gut health, metabolism), Zhang (anti-inflammation, kidney protection), 431 (immunity, respiratory health), 01 (type 2 diabetes management), DN-114001 (immunity). Choose strains according to application scenarios.
Q2: What benefits does Lactobacillus casei bring to the intestines?
A: It regulates gut microbiota balance, increases beneficial bacteria, reduces pro-inflammatory factors, elevates short-chain fatty acids, alleviates colitis, and improves constipation and diarrhea.
Q3: Can Lactobacillus casei boost immunity?
A: Yes. Strain 431 has been clinically proven to shorten the duration of upper respiratory symptoms in adults from 7.3 days to 6.4 days.
Q4: Is Lactobacillus casei beneficial for metabolic health?
A: Yes. Strains including LC2W, 431 and 01 can improve body weight, blood glucose, insulin and triglyceride levels, and assist in type 2 diabetes management.
Q5: Can Lactobacillus casei protect the kidneys?
A: Strain Zhang has been verified in animal and clinical studies to alleviate kidney injury, slow the progression of chronic kidney disease, and exhibits excellent tolerability.
